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Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome
The interleukin-1 (IL-1) family of cytokines has been implicated in the pathogenesis of atherosclerosis in previous studies. The NLRP3 inflammasome has recently emerged as a pivotal regulator of IL-1β maturation and secretion by macrophages. Little is currently known about a possible role for the NL...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101814/ https://www.ncbi.nlm.nih.gov/pubmed/21451572 http://dx.doi.org/10.1038/cddis.2011.18 |