Cargando…

Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

The interleukin-1 (IL-1) family of cytokines has been implicated in the pathogenesis of atherosclerosis in previous studies. The NLRP3 inflammasome has recently emerged as a pivotal regulator of IL-1β maturation and secretion by macrophages. Little is currently known about a possible role for the NL...

Descripción completa

Detalles Bibliográficos
Autores principales: Menu, P, Pellegrin, M, Aubert, J-F, Bouzourene, K, Tardivel, A, Mazzolai, L, Tschopp, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101814/
https://www.ncbi.nlm.nih.gov/pubmed/21451572
http://dx.doi.org/10.1038/cddis.2011.18