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PERP expression stabilizes active p53 via modulation of p53-MDM2 interaction in uveal melanoma cells

The activation and regulation of target genes by the tumour-suppressor p53 dictates the fate of a cell, with cell cycle arrest or apoptosis being two distinct outcomes. PERP (p53 apoptosis effector related to PMP-22), a p53 transcriptional target, is induced specifically during apoptosis but not cel...

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Detalles Bibliográficos
Autores principales:	Davies, L, Spiller, D, White, M R H, Grierson, I, Paraoan, L
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101815/ https://www.ncbi.nlm.nih.gov/pubmed/21451571 http://dx.doi.org/10.1038/cddis.2011.19

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