Ras mutation cooperates with β-catenin activation to drive bladder tumourigenesis

Mutations in the Ras family of proteins (predominantly in H-Ras) occur in approximately 40% of urothelial cell carcinoma (UCC). However, relatively little is known about subsequent mutations/pathway alterations that allow tumour progression. Indeed, expressing mutant H-Ras within the mouse bladder d...

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Detalles Bibliográficos
Autores principales: Ahmad, I, Patel, R, Liu, Y, Singh, L B, Taketo, M M, Wu, X-R, Leung, H Y, Sansom, O J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101820/
https://www.ncbi.nlm.nih.gov/pubmed/21368895
http://dx.doi.org/10.1038/cddis.2011.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101820/
https://www.ncbi.nlm.nih.gov/pubmed/21368895
http://dx.doi.org/10.1038/cddis.2011.7

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