Individual caspase-10 isoforms play distinct and opposing roles in the initiation of death receptor-mediated tumour cell apoptosis

The cysteine protease caspase-8 is an essential executioner of the death receptor (DR) apoptotic pathway. The physiological function of its homologue caspase-10 remains poorly understood, and the ability of caspase-10 to substitute for caspase-8 in the DR apoptotic pathway is still controversial. He...

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Detalles Bibliográficos
Autores principales: Mühlethaler-Mottet, A, Flahaut, M, Bourloud, K Balmas, Nardou, K, Coulon, A, Liberman, J, Thome, M, Gross, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101821/
https://www.ncbi.nlm.nih.gov/pubmed/21368896
http://dx.doi.org/10.1038/cddis.2011.8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101821/
https://www.ncbi.nlm.nih.gov/pubmed/21368896
http://dx.doi.org/10.1038/cddis.2011.8

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