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Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis
DNA damage signaling pathways are initiated in response to chemical reagents and radiation damage, as well as in response to hypoxia. It is implicated that structural maintenance of chromosomes 1 (SMC1) is not only a component of the cohesion complex but also facilitates the activation of DNA damage...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101822/ https://www.ncbi.nlm.nih.gov/pubmed/21390062 http://dx.doi.org/10.1038/cddis.2011.9 |