Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infection

Mycobacterium tuberculosis (Mtb) has generated a global health catastrophe that has been compounded by the emergence of drug resistant Mtb strains. We used whole genome sequencing to compare the accumulation of mutations in Mtb isolated from cynomolgus macaques with active, latent and reactivated di...

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Detalles Bibliográficos
Autores principales: Ford, Christopher B., Lin, Philana Ling, Chase, Michael, Shah, Rupal R., Iartchouk, Oleg, Galagan, James, Mohaideen, Nilofar, Ioerger, Thomas R., Sacchettini, James C., Lipsitch, Marc, Flynn, JoAnne L., Fortune, Sarah M.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101871/
https://www.ncbi.nlm.nih.gov/pubmed/21516081
http://dx.doi.org/10.1038/ng.811

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101871/
https://www.ncbi.nlm.nih.gov/pubmed/21516081
http://dx.doi.org/10.1038/ng.811

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