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Testosterone regulates cell proliferation in aggressive fibromatosis (desmoid tumour)

BACKGROUND: Aggressive fibromatosis (desmoid tumour) is a locally invasive tumour caused by mutations resulting in β-catenin protein stabilisation. Apc1638N mice are predisposed to developing aggressive fibromatosis tumours, and male mice develop greater numbers of tumours than female mice, suggesti...

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Detalles Bibliográficos
Autores principales: Hong, H, Nadesan, P, Poon, R, Alman, B A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101926/
https://www.ncbi.nlm.nih.gov/pubmed/21468052
http://dx.doi.org/10.1038/bjc.2011.107