Downregulation of transcription factor SOX2 in cancer stem cells suppresses growth and metastasis of lung cancer

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BACKGROUND: The cancer stem cell hypothesis suggests that neoplastic clones are maintained exclusively by a small subpopulation of cells, which have indefinite proliferation and differentiation potentials and give rise to phenotypically diverse cancer cells. Cancer stem cells have been isolated by t...

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Detalles Bibliográficos
Autores principales: Xiang, R, Liao, D, Cheng, T, Zhou, H, Shi, Q, Chuang, T S, Markowitz, D, Reisfeld, R A, Luo, Y
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101944/
https://www.ncbi.nlm.nih.gov/pubmed/21468047
http://dx.doi.org/10.1038/bjc.2011.94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101944/
https://www.ncbi.nlm.nih.gov/pubmed/21468047
http://dx.doi.org/10.1038/bjc.2011.94

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