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Origin of bistability underlying mammalian cell cycle entry
Precise control of cell proliferation is fundamental to tissue homeostasis and differentiation. Mammalian cells commit to proliferation at the restriction point (R-point). It has long been recognized that the R-point is tightly regulated by the Rb–E2F signaling pathway. Our recent work has further d...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101952/ https://www.ncbi.nlm.nih.gov/pubmed/21525871 http://dx.doi.org/10.1038/msb.2011.19 |