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Is the variant c.422+90G→A in intron 4 of indoleamine 2, 3 -dioxygenase (IDO) gene related to age related cataracts?
PURPOSE: To screen for sequence variations in the IDO gene that encodes indoleamine 2, 3- dioxygenase (IDO), the first rate limiting enzyme involved in the tryptophan catabolism which results in the production of UV filters playing a role in the maintenance of lens transparency. METHODS: We conducte...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102029/ https://www.ncbi.nlm.nih.gov/pubmed/21617756 |