Antiviral Activity of 3(2H)- and 6-Chloro-3(2H)-Isoflavenes against Highly Diverged, Neurovirulent Vaccine-Derived, Type2 Poliovirus Sewage Isolates

BACKGROUND: Substituted flavanoids interfere with uncoating of Enteroviruses including Sabin-2 polio vaccine strains. However flavanoid resistant and dependent, type-2 polio vaccine strains (minimally-diverged), emerged during in vitro infections. Between 1998–2009, highly-diverged (8 to >15%) ty...

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Detalles Bibliográficos
Autores principales: Shulman, Lester M., Sofer, Danit, Manor, Yossi, Mendelson, Ella, Balanant, Jean, Salvati, Anna Laura, Delpeyroux, Francis, Fiore, Lucia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102060/
https://www.ncbi.nlm.nih.gov/pubmed/21904594
http://dx.doi.org/10.1371/journal.pone.0018360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102060/
https://www.ncbi.nlm.nih.gov/pubmed/21904594
http://dx.doi.org/10.1371/journal.pone.0018360

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