Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells

We evaluated the mechanism of capsaicin-mediated ROS generation in pancreatic cancer cells. The generation of ROS was about 4–6 fold more as compared to control and as early as 1 h after capsaicin treatment in BxPC-3 and AsPC-1 cells but not in normal HPDE-6 cells. The generation of ROS was inhibite...

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Detalles Bibliográficos
Autores principales: Pramanik, Kartick C., Boreddy, Srinivas Reddy, Srivastava, Sanjay K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102063/
https://www.ncbi.nlm.nih.gov/pubmed/21647434
http://dx.doi.org/10.1371/journal.pone.0020151

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102063/
https://www.ncbi.nlm.nih.gov/pubmed/21647434
http://dx.doi.org/10.1371/journal.pone.0020151

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