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Simultaneous Visualization of Both Signaling Cascade Activity and End-Point Gene Expression in Single Cells
We have developed an approach for simultaneous detection of individual endogenous protein modifications and mRNA molecules in single cells in situ. For this purpose we combined two methods previously developed in our lab: in situ proximity ligation assay for the detection of individual protein inter...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102075/ https://www.ncbi.nlm.nih.gov/pubmed/21647446 http://dx.doi.org/10.1371/journal.pone.0020148 |