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Distinct CD4(+)CD8(+) Double-Positive T Cells in the Blood and Liver of Patients during Chronic Hepatitis B and C

CD4(+) and CD8(+) T cells, the main effectors of adaptive cellular immune responses, differentiate from immature, non-functional CD4(+)CD8(+) double-positive T (DPT) cells in the thymus. Increased proportions of circulating DPT lymphocytes have been observed during acute viral infections; in chronic...

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Detalles Bibliográficos
Autores principales: Nascimbeni, Michelina, Pol, Stanislas, Saunier, Bertrand
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102078/
https://www.ncbi.nlm.nih.gov/pubmed/21647449
http://dx.doi.org/10.1371/journal.pone.0020145