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Distinct CD4(+)CD8(+) Double-Positive T Cells in the Blood and Liver of Patients during Chronic Hepatitis B and C
CD4(+) and CD8(+) T cells, the main effectors of adaptive cellular immune responses, differentiate from immature, non-functional CD4(+)CD8(+) double-positive T (DPT) cells in the thymus. Increased proportions of circulating DPT lymphocytes have been observed during acute viral infections; in chronic...
Autores principales: | Nascimbeni, Michelina, Pol, Stanislas, Saunier, Bertrand |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102078/ https://www.ncbi.nlm.nih.gov/pubmed/21647449 http://dx.doi.org/10.1371/journal.pone.0020145 |
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