Interaction between Amyloid Beta Peptide and an Aggregation Blocker Peptide Mimicking Islet Amyloid Polypeptide

Assembly of amyloid-beta peptide (Aβ) into cytotoxic oligomeric and fibrillar aggregates is believed to be a major pathologic event in Alzheimer's disease (AD) and interfering with Aβ aggregation is an important strategy in the development of novel therapeutic approaches. Prior studies have sho...

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Detalles Bibliográficos
Autores principales: Rezaei-Ghaleh, Nasrollah, Andreetto, Erika, Yan, Li-Mei, Kapurniotu, Aphrodite, Zweckstetter, Markus
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102090/
https://www.ncbi.nlm.nih.gov/pubmed/21633500
http://dx.doi.org/10.1371/journal.pone.0020289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102090/
https://www.ncbi.nlm.nih.gov/pubmed/21633500
http://dx.doi.org/10.1371/journal.pone.0020289

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