Cargando…
Interaction between Amyloid Beta Peptide and an Aggregation Blocker Peptide Mimicking Islet Amyloid Polypeptide
Assembly of amyloid-beta peptide (Aβ) into cytotoxic oligomeric and fibrillar aggregates is believed to be a major pathologic event in Alzheimer's disease (AD) and interfering with Aβ aggregation is an important strategy in the development of novel therapeutic approaches. Prior studies have sho...
Autores principales: | Rezaei-Ghaleh, Nasrollah, Andreetto, Erika, Yan, Li-Mei, Kapurniotu, Aphrodite, Zweckstetter, Markus |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102090/ https://www.ncbi.nlm.nih.gov/pubmed/21633500 http://dx.doi.org/10.1371/journal.pone.0020289 |
Ejemplares similares
-
The Human Host‐Defense Peptide Cathelicidin LL‐37 is a Nanomolar Inhibitor of Amyloid Self‐Assembly of Islet Amyloid Polypeptide (IAPP)
por: Armiento, Valentina, et al.
Publicado: (2020) -
Early Divergence in Misfolding Pathways of Amyloid‐Beta Peptides
por: Mamone, Salvatore, et al.
Publicado: (2021) -
The Amyloid Forming Peptides Islet Amyloid Polypeptide and Amyloid β Interact at the Molecular Level
por: Wang, Ye, et al.
Publicado: (2021) -
Islet amyloid polypeptide & amyloid beta peptide roles in Alzheimer’s disease: two triggers, one disease
por: Ferreira, Sofia, et al.
Publicado: (2020) -
Reorientational Dynamics of Amyloid-β
from NMR Spin Relaxation and Molecular Simulation
por: Rezaei-Ghaleh, Nasrollah, et al.
Publicado: (2019)