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GLI1 Confers Profound Phenotypic Changes upon LNCaP Prostate Cancer Cells That Include the Acquisition of a Hormone Independent State

The GLI (GLI1/GLI2) transcription factors have been implicated in the development and progression of prostate cancer although our understanding of how they actually contribute to the biology of these common tumours is limited. We observed that GLI reporter activity was higher in normal (PNT-2) and t...

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Detalles Bibliográficos
Autores principales: Nadendla, Sandeep K., Hazan, Allon, Ward, Matt, Harper, Lisa J., Moutasim, Karwan, Bianchi, Lucia S., Naase, Mahmoud, Ghali, Lucy, Thomas, Gareth J., Prowse, David M., Philpott, Michael P., Neill, Graham W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102098/
https://www.ncbi.nlm.nih.gov/pubmed/21633508
http://dx.doi.org/10.1371/journal.pone.0020271