Triostin A derived hybrid for simultaneous DNA binding and metal coordination

The natural product triostin A is known as an antibiotic based on specific DNA recognition. Structurally, a bicyclic depsipeptide backbone provides a well-defined scaffold preorganizing the recognition motifs for bisintercalation. Replacing the intercalating quinoxaline moieties of triostin A by nuc...

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Detalles Bibliográficos
Autores principales: Sachs, Eike-F., Nadler, André, Diederichsen, Ulf
Formato: Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102191/
https://www.ncbi.nlm.nih.gov/pubmed/20967559
http://dx.doi.org/10.1007/s00726-010-0764-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102191/
https://www.ncbi.nlm.nih.gov/pubmed/20967559
http://dx.doi.org/10.1007/s00726-010-0764-3

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