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Triostin A derived hybrid for simultaneous DNA binding and metal coordination

The natural product triostin A is known as an antibiotic based on specific DNA recognition. Structurally, a bicyclic depsipeptide backbone provides a well-defined scaffold preorganizing the recognition motifs for bisintercalation. Replacing the intercalating quinoxaline moieties of triostin A by nuc...

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Detalles Bibliográficos
Autores principales:	Sachs, Eike-F., Nadler, André, Diederichsen, Ulf
Formato:	Texto
Lenguaje:	English
Publicado:	Springer Vienna 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102191/ https://www.ncbi.nlm.nih.gov/pubmed/20967559 http://dx.doi.org/10.1007/s00726-010-0764-3

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