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Emerging role of carfilzomib in treatment of relapsed and refractory lymphoid neoplasms and multiple myeloma

Proteasome inhibition forms the cornerstone of antimyeloma therapy. The first-in-class proteasome inhibitor, bortezomib, either alone or in combination with other chemotherapeutic agents, induces high overall response rates and response qualities in patients with clinically and molecularly defined h...

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Detalles Bibliográficos
Autores principales: Jain, Salvia, Diefenbach, Catherine, Zain, Jasmine, O’Connor, Owen A
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102580/
https://www.ncbi.nlm.nih.gov/pubmed/21654882
http://dx.doi.org/10.2147/CE.S13838