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Neopterin production and tryptophan degradation during 24-months therapy with interferon beta-1a in multiple sclerosis patients
BACKGROUND: Increased synthesis of neopterin and degradation of tryptophan to kynurenine, measured as kynurenine/tryptophan ratio (kyn/trp ratio), are considered in vitro markers of interferon beta-1a (IFNβ-1a) activity. The aim of the study was to investigate the dynamic profile of neopterin and ky...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102623/ https://www.ncbi.nlm.nih.gov/pubmed/21501517 http://dx.doi.org/10.1186/1479-5876-9-42 |