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Function modification of SR-PSOX by point mutations of basic amino acids

BACKGROUND: Atherosclerosis (AS) is a common cardiovascular disease. Transformation of macrophages to form foam cells by internalizing modified low density-lipoprotein (LDL) via scavenger receptor (SR) is a key pathogenic process in the onset of AS. It has been demonstrated that SR-PSOX functions as...

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Detalles Bibliográficos
Autores principales: Liu, Weiwei, Yin, Lan, Chen, Chunxia, Dai, Yalei
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102630/
https://www.ncbi.nlm.nih.gov/pubmed/21492481
http://dx.doi.org/10.1186/1476-511X-10-59