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Allele-Specific, Age-Dependent and BMI-Associated DNA Methylation of Human MCHR1

BACKGROUND: Melanin-concentrating hormone receptor 1 (MCHR1) plays a significant role in regulation of energy balance, food intake, physical activity and body weight in humans and rodents. Several association studies for human obesity showed contrary results concerning the SNPs rs133072 (G/A) and rs...

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Detalles Bibliográficos
Autores principales: Stepanow, Stefanie, Reichwald, Kathrin, Huse, Klaus, Gausmann, Ulrike, Nebel, Almut, Rosenstiel, Philip, Wabitsch, Martin, Fischer-Posovszky, Pamela, Platzer, Matthias
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102661/
https://www.ncbi.nlm.nih.gov/pubmed/21637341
http://dx.doi.org/10.1371/journal.pone.0017711