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Role of IL-1 Beta in the Development of Human T(H)17 Cells: Lesson from NLPR3 Mutated Patients
BACKGROUND: T helper 17 cells (T(H)-17) represent a lineage of effector T cells critical in host defence and autoimmunity. In both mouse and human IL-1β has been indicated as a key cytokine for the commitment to T(H)-17 cells. Cryopyrin-associated periodic syndromes (CAPS) are a group of inflammator...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102666/ https://www.ncbi.nlm.nih.gov/pubmed/21637346 http://dx.doi.org/10.1371/journal.pone.0020014 |