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Role of IL-1 Beta in the Development of Human T(H)17 Cells: Lesson from NLPR3 Mutated Patients

BACKGROUND: T helper 17 cells (T(H)-17) represent a lineage of effector T cells critical in host defence and autoimmunity. In both mouse and human IL-1β has been indicated as a key cytokine for the commitment to T(H)-17 cells. Cryopyrin-associated periodic syndromes (CAPS) are a group of inflammator...

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Detalles Bibliográficos
Autores principales:	Lasigliè, Denise, Traggiai, Elisabetta, Federici, Silvia, Alessio, Maria, Buoncompagni, Antonella, Accogli, Andrea, Chiesa, Sabrina, Penco, Federica, Martini, Alberto, Gattorno, Marco
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102666/ https://www.ncbi.nlm.nih.gov/pubmed/21637346 http://dx.doi.org/10.1371/journal.pone.0020014

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