Identification of Novel Targets of CSL-Dependent Notch Signaling in Hematopoiesis

Somatic activating mutations in the Notch1 receptor result in the overexpression of activated Notch1, which can be tumorigenic. The goal of this study is to understand the molecular mechanisms underlying the phenotypic changes caused by the overexpression of ligand independent Notch 1 by using a tet...

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Detalles Bibliográficos
Autores principales: Hamidi, Habib, Gustafason, Derek, Pellegrini, Matteo, Gasson, Judith
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102675/
https://www.ncbi.nlm.nih.gov/pubmed/21637838
http://dx.doi.org/10.1371/journal.pone.0020022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102675/
https://www.ncbi.nlm.nih.gov/pubmed/21637838
http://dx.doi.org/10.1371/journal.pone.0020022

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