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Identification of Novel Targets of CSL-Dependent Notch Signaling in Hematopoiesis
Somatic activating mutations in the Notch1 receptor result in the overexpression of activated Notch1, which can be tumorigenic. The goal of this study is to understand the molecular mechanisms underlying the phenotypic changes caused by the overexpression of ligand independent Notch 1 by using a tet...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102675/ https://www.ncbi.nlm.nih.gov/pubmed/21637838 http://dx.doi.org/10.1371/journal.pone.0020022 |