Expression of miRNAs miR-133b and miR-206 in the Il17a/f Locus Is Co-Regulated with IL-17 Production in αβ and γδ T Cells

Differentiation of T helper 17 cells (Th17) is a multistep process that involves the cytokines IL-6, TGF-β, and IL-23 as well as IL-1β, IL-21, and TNF-α. Thereby, robust induction of the capacity to produce IL-17 involves epigenetic modifications of the syntenic Il17a/f locus. Using inbred mouse str...

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Detalles Bibliográficos
Autores principales: Haas, Jan D., Nistala, Kiran, Petermann, Franziska, Saran, Namita, Chennupati, Vijaykumar, Schmitz, Susanne, Korn, Thomas, Wedderburn, Lucy R., Förster, Reinhold, Krueger, Andreas, Prinz, Immo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102691/
https://www.ncbi.nlm.nih.gov/pubmed/21637854
http://dx.doi.org/10.1371/journal.pone.0020171

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102691/
https://www.ncbi.nlm.nih.gov/pubmed/21637854
http://dx.doi.org/10.1371/journal.pone.0020171

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