A Zebrafish Model of Roberts Syndrome Reveals That Esco2 Depletion Interferes with Development by Disrupting the Cell Cycle

The human developmental diseases Cornelia de Lange Syndrome (CdLS) and Roberts Syndrome (RBS) are both caused by mutations in proteins responsible for sister chromatid cohesion. Cohesion is mediated by a multi-subunit complex called cohesin, which is loaded onto chromosomes by NIPBL. Once on chromos...

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Detalles Bibliográficos
Autores principales: Mönnich, Maren, Kuriger, Zoë, Print, Cristin G., Horsfield, Julia A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102698/
https://www.ncbi.nlm.nih.gov/pubmed/21637801
http://dx.doi.org/10.1371/journal.pone.0020051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102698/
https://www.ncbi.nlm.nih.gov/pubmed/21637801
http://dx.doi.org/10.1371/journal.pone.0020051

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