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Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence

In cell senescence, cultured cells cease proliferating and acquire aberrant gene expression patterns. MicroRNAs (miRNAs) modulate gene expression through translational repression or mRNA degradation and have been implicated in senescence. We used deep sequencing to carry out a comprehensive survey o...

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Detalles Bibliográficos
Autores principales: Dhahbi, Joseph M., Atamna, Hani, Boffelli, Dario, Magis, Wendy, Spindler, Stephen R., Martin, David I. K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102725/
https://www.ncbi.nlm.nih.gov/pubmed/21637828
http://dx.doi.org/10.1371/journal.pone.0020509