Promoter Methylation in Head and Neck Squamous Cell Carcinoma Cell Lines Is Significantly Different than Methylation in Primary Tumors and Xenografts

Studies designed to identify novel methylation events related to cancer often employ cancer cell lines in the discovery phase of the experiments and have a relatively low rate of discovery of cancer-related methylation events. An alternative algorithm for discovery of novel methylation in cancer use...

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Detalles Bibliográficos
Autores principales: Hennessey, Patrick T., Ochs, Michael F., Mydlarz, Wojciech W., Hsueh, Wayne, Cope, Leslie, Yu, Wayne, Califano, Joseph A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102742/
https://www.ncbi.nlm.nih.gov/pubmed/21637785
http://dx.doi.org/10.1371/journal.pone.0020584

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102742/
https://www.ncbi.nlm.nih.gov/pubmed/21637785
http://dx.doi.org/10.1371/journal.pone.0020584

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