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Nodal-Dependent Mesendoderm Specification Requires the Combinatorial Activities of FoxH1 and Eomesodermin

Vertebrate mesendoderm specification requires the Nodal signaling pathway and its transcriptional effector FoxH1. However, loss of FoxH1 in several species does not reliably cause the full range of loss-of-Nodal phenotypes, indicating that Nodal signals through additional transcription factors durin...

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Detalles Bibliográficos
Autores principales: Slagle, Christopher E., Aoki, Tsutomu, Burdine, Rebecca D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102743/
https://www.ncbi.nlm.nih.gov/pubmed/21637786
http://dx.doi.org/10.1371/journal.pgen.1002072