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Integrated Genome-Scale Prediction of Detrimental Mutations in Transcription Networks
A central challenge in genetics is to understand when and why mutations alter the phenotype of an organism. The consequences of gene inhibition have been systematically studied and can be predicted reasonably well across a genome. However, many sequence variants important for disease and evolution m...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102745/ https://www.ncbi.nlm.nih.gov/pubmed/21637788 http://dx.doi.org/10.1371/journal.pgen.1002077 |