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A Novel Mouse Synaptonemal Complex Protein Is Essential for Loading of Central Element Proteins, Recombination, and Fertility

The synaptonemal complex (SC) is a proteinaceous, meiosis-specific structure that is highly conserved in evolution. During meiosis, the SC mediates synapsis of homologous chromosomes. It is essential for proper recombination and segregation of homologous chromosomes, and therefore for genome haploid...

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Detalles Bibliográficos
Autores principales: Schramm, Sabine, Fraune, Johanna, Naumann, Ronald, Hernandez-Hernandez, Abrahan, Höög, Christer, Cooke, Howard J., Alsheimer, Manfred, Benavente, Ricardo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102746/
https://www.ncbi.nlm.nih.gov/pubmed/21637789
http://dx.doi.org/10.1371/journal.pgen.1002088