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A Novel Mouse Synaptonemal Complex Protein Is Essential for Loading of Central Element Proteins, Recombination, and Fertility
The synaptonemal complex (SC) is a proteinaceous, meiosis-specific structure that is highly conserved in evolution. During meiosis, the SC mediates synapsis of homologous chromosomes. It is essential for proper recombination and segregation of homologous chromosomes, and therefore for genome haploid...
Autores principales: | Schramm, Sabine, Fraune, Johanna, Naumann, Ronald, Hernandez-Hernandez, Abrahan, Höög, Christer, Cooke, Howard J., Alsheimer, Manfred, Benavente, Ricardo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102746/ https://www.ncbi.nlm.nih.gov/pubmed/21637789 http://dx.doi.org/10.1371/journal.pgen.1002088 |
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