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Structural and Functional Differences in the Long Non-Coding RNA Hotair in Mouse and Human

Long non-coding RNAs regulate various biological processes such as dosage compensation, imprinting, and chromatin organization. HOTAIR, a paradigm of this new class of RNAs, is localized within the human HOXC gene cluster and was shown, in human cells, to regulate HOXD genes in trans via the recruit...

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Detalles Bibliográficos
Autores principales: Schorderet, Patrick, Duboule, Denis
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102750/
https://www.ncbi.nlm.nih.gov/pubmed/21637793
http://dx.doi.org/10.1371/journal.pgen.1002071