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TGF-β-induced IRAK-M Expression in Tumor Associated Macrophages Regulates Lung Tumor Growth

Tumor associated macrophages (TAMs) constitute a major component of the immune cell infiltrate observed in the tumor microenvironment (TME). Factors present in the TME including TGF-β, allow tumors to circumvent host mediated immune responses to promote tumor progression. However, the molecular mech...

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Detalles Bibliográficos
Autores principales: Standiford, Theodore J., Kuick, Rork, Bhan, Urvashi, Chen, Jun, Newstead, Michael, Keshamouni, Venkateshwar G.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102782/
https://www.ncbi.nlm.nih.gov/pubmed/21278795
http://dx.doi.org/10.1038/onc.2010.619