Neuronal activity regulates the regional vulnerability to amyloid-β deposition

Amyloid-β (Aβ) plaque deposition in specific brain regions is a major pathological hallmark of Alzheimer’fs disease (AD). However, the mechanism underlying the regional vulnerability to Aβ deposition in AD is unknown. Herein, we provide evidence that endogenous neuronal activity regulates the region...

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Detalles Bibliográficos
Autores principales: Bero, Adam W., Yan, Ping, Roh, Jee Hoon, Cirrito, John R., Stewart, Floy R., Raichle, Marcus E., Lee, Jin-Moo, Holtzman, David M.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102784/
https://www.ncbi.nlm.nih.gov/pubmed/21532579
http://dx.doi.org/10.1038/nn.2801

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102784/
https://www.ncbi.nlm.nih.gov/pubmed/21532579
http://dx.doi.org/10.1038/nn.2801

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