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Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex

Projection neurons migrate from the ventricular zone to the neocortical plate during mouse brain development. Their overall movement is radial, but they become multipolar and move non-radially in the intermediate zone. Here we show that Reelin, the Rap1 GTPase, and N-cadherin (NCad) are important fo...

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Detalles Bibliográficos
Autores principales: Jossin, Yves, Cooper, Jonathan A.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102785/
https://www.ncbi.nlm.nih.gov/pubmed/21516100
http://dx.doi.org/10.1038/nn.2816