Mechanism of CaMKII regulation of AMPA receptor gating

The function, trafficking and synaptic signalling of AMPA receptors are tightly regulated by phosphorylation. CaMKII phosphorylates the GluA1 AMPA subunit at Ser831 to increase single channel conductance. We show for the first time that CaMKII increases the conductance of native heteromeric AMPA rec...

Descripción completa

Detalles Bibliográficos
Autores principales: Kristensen, Anders S., Jenkins, Meagan A., Banke, Tue G., Schousboe, Arne, Makino, Yuichi, Johnson, Richard C., Huganir, Richard, Traynelis, Stephen F.
Formato: Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102786/
https://www.ncbi.nlm.nih.gov/pubmed/21516102
http://dx.doi.org/10.1038/nn.2804

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102786/
https://www.ncbi.nlm.nih.gov/pubmed/21516102
http://dx.doi.org/10.1038/nn.2804

Ejemplares similares