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Identification strategy for unknown pollutants using high-resolution mass spectrometry: Androgen-disrupting compounds identified through effect-directed analysis

Effect-directed analysis has been applied to a river sediment sample of concern to identify the compounds responsible for the observed effects in an in vitro (anti-)androgenicity assay. For identification after non-target analysis performed on a high-resolution LTQ-Orbitrap, we developed a de novo i...

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Detalles Bibliográficos
Autores principales: Weiss, Jana M., Simon, Eszter, Stroomberg, Gerard J., de Boer, Ronald, de Boer, Jacob, van der Linden, Sander C., Leonards, Pim E. G., Lamoree, Marja H.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3102845/
https://www.ncbi.nlm.nih.gov/pubmed/21505951
http://dx.doi.org/10.1007/s00216-011-4939-x