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Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo
Glucosidase II (GII) sequentially removes the two innermost glucose residues from the glycan (Glc(3)Man(9)GlcNAc(2)) transferred to proteins. GII also participates in cycles involving the lectin/chaperones calnexin (CNX) and calreticulin (CRT) as it removes the single glucose unit added to folding i...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103398/ https://www.ncbi.nlm.nih.gov/pubmed/21471007 http://dx.doi.org/10.1091/mbc.E11-01-0019 |