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Glucosidase II and N-glycan mannose content regulate the half-lives of monoglucosylated species in vivo

Glucosidase II (GII) sequentially removes the two innermost glucose residues from the glycan (Glc(3)Man(9)GlcNAc(2)) transferred to proteins. GII also participates in cycles involving the lectin/chaperones calnexin (CNX) and calreticulin (CRT) as it removes the single glucose unit added to folding i...

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Detalles Bibliográficos
Autores principales: Stigliano, Ivan D., Alculumbre, Solana G., Labriola, Carlos A., Parodi, Armando J., D'Alessio, Cecilia
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103398/
https://www.ncbi.nlm.nih.gov/pubmed/21471007
http://dx.doi.org/10.1091/mbc.E11-01-0019

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