Production of N(α)-acetylated thymosin α1 in Escherichia coli

BACKGROUND: Thymosin α1 (Tα1), a 28-amino acid N(α)-acetylated peptide, has a powerful general immunostimulating activity. Although biosynthesis is an attractive means of large-scale manufacture, to date, Tα1 can only be chemosynthesized because of two obstacles to its biosynthesis: the difficulties...

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Detalles Bibliográficos
Autores principales: Ren, Yuantao, Yao, Xueqin, Dai, Hongmei, Li, Shulong, Fang, Hongqing, Chen, Huipeng, Zhou, Changlin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103413/
https://www.ncbi.nlm.nih.gov/pubmed/21513520
http://dx.doi.org/10.1186/1475-2859-10-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103413/
https://www.ncbi.nlm.nih.gov/pubmed/21513520
http://dx.doi.org/10.1186/1475-2859-10-26

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