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Production of N(α)-acetylated thymosin α1 in Escherichia coli
BACKGROUND: Thymosin α1 (Tα1), a 28-amino acid N(α)-acetylated peptide, has a powerful general immunostimulating activity. Although biosynthesis is an attractive means of large-scale manufacture, to date, Tα1 can only be chemosynthesized because of two obstacles to its biosynthesis: the difficulties...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103413/ https://www.ncbi.nlm.nih.gov/pubmed/21513520 http://dx.doi.org/10.1186/1475-2859-10-26 |