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Potential errors in conventional DOT measurement techniques in shake flasks and verification using a rotating flexitube optical sensor

BACKGROUND: Dissolved oxygen tension (DOT) is an important parameter for evaluating a bioprocess. Conventional means to measure DOT in shake flasks using fixed Clark-type electrodes immersed in the bulk liquid are problematic, because they inherently alter the hydrodynamics of the systems. Other app...

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Detalles Bibliográficos
Autores principales: Hansen, Sven, Kensy, Frank, Käser, Andreas, Büchs, Jochen
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103429/
https://www.ncbi.nlm.nih.gov/pubmed/21569304
http://dx.doi.org/10.1186/1472-6750-11-49