Bioactivities of berberine metabolites after transformation through CYP450 isoenzymes

BACKGROUND: Berberine (BBR) is a drug with multiple effects on cellular energy metabolism. The present study explored answers to the question of which CYP450 (Cytochrome P450) isoenzymes execute the phase-I transformation for BBR, and what are the bioactivities of its metabolites on energy pathways....

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Detalles Bibliográficos
Autores principales: Li, Yi, Ren, Gang, Wang, Yan-Xiang, Kong, Wei-Jia, Yang, Peng, Wang, Yue-Ming, Li, Ying-Hong, Yi, Hong, Li, Zhuo-Rong, Song, Dan-Qing, Jiang, Jian-Dong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103436/
https://www.ncbi.nlm.nih.gov/pubmed/21569619
http://dx.doi.org/10.1186/1479-5876-9-62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103436/
https://www.ncbi.nlm.nih.gov/pubmed/21569619
http://dx.doi.org/10.1186/1479-5876-9-62

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