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Myomegalin is a novel A-kinase anchoring protein involved in the phosphorylation of cardiac myosin binding protein C

BACKGROUND: Cardiac contractility is regulated by dynamic phosphorylation of sarcomeric proteins by kinases such as cAMP-activated protein kinase A (PKA). Efficient phosphorylation requires that PKA be anchored close to its targets by A-kinase anchoring proteins (AKAPs). Cardiac Myosin Binding Prote...

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Detalles Bibliográficos
Autores principales: Uys, Gerrida M, Ramburan, Amsha, Loos, Benjamin, Kinnear, Craig J, Korkie, Lundi J, Mouton, Jomien, Riedemann, Johann, Moolman-Smook, Johanna C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103437/
https://www.ncbi.nlm.nih.gov/pubmed/21569246
http://dx.doi.org/10.1186/1471-2121-12-18