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Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies

BACKGROUND: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improved, the difficulty of de novo genome assembly has increased, due in large part to the shorter reads generated by the new t...

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Detalles Bibliográficos
Autores principales: Wetzel, Joshua, Kingsford, Carl, Pop, Mihai
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103447/
https://www.ncbi.nlm.nih.gov/pubmed/21486487
http://dx.doi.org/10.1186/1471-2105-12-95