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Assessing the benefits of using mate-pairs to resolve repeats in de novo short-read prokaryotic assemblies
BACKGROUND: Next-generation sequencing technologies allow genomes to be sequenced more quickly and less expensively than ever before. However, as sequencing technology has improved, the difficulty of de novo genome assembly has increased, due in large part to the shorter reads generated by the new t...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103447/ https://www.ncbi.nlm.nih.gov/pubmed/21486487 http://dx.doi.org/10.1186/1471-2105-12-95 |